Teaching NeuroImages: Neuroradiologic evolution of Leigh disease
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چکیده
منابع مشابه
Teaching NeuroImages: Neuroradiologic evolution of Leigh disease
A 2-year-old girl with no significant family history presented with motor developmental delay and strabismus. MRI revealed unilateral basal ganglia and brainstem lesions (figure 1). Eighteen months later, she developed acute onset right arm weakness, leading to a diagnosis of multiphasic disseminated encephalomyelitis. Treatment with steroids and mycophenolate produced no symptomatic or imaging...
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A 58-year-old woman presented with subacute onset of tetraparesis, anarthria, and dysphagia after rapid correction of hyponatremia caused by repeated vomiting. Brain MRI showed pontine and extrapontine lesions typical for the osmotic demyelination syndrome (figure, A and B). The pontine lesion showed nonhomogeneous contrast enhancement (figure, C), which diminished after 15 days (figure, D). Ba...
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A 57-year-old man presented with a 4-week history of fever, visual loss, and progressive ataxic gait. He worked as a truck driver and had been in contact with raw sheepskin a few months prior. Neurologic examination showed drowsiness, pseudobulbar syndrome, hyperreflexia, ataxia, and optic disc edema. He had a lymphocytic pleocytosis and diffuse hyperintense white matter lesions on brain MRI (f...
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A 30-year-old man presented with recurrent headaches. CT head revealed a clival chordoma (figure 1A). Chordomas originate from the embryonic remnants of the notochord and account for 2%–4% of all malignant bone tumors. They have a predilection for the axial skeleton, with 35% affecting the spheno-occipital region. The incidence peaks at ages 20–40 years. Male patients are affected twice Figure ...
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ژورنال
عنوان ژورنال: Neurology
سال: 2016
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000003182